A Search for Obligatory Paternal Alleles in a DNA Database to Find an Alleged Rapist in a Fatherless Paternity Case

作者：Barash Mark^*; Reshef Ayeleth; Voskoboinik Lev; Zamir Ashira; Motro Uzi; Gafny Ron

来源：Journal of Forensic Sciences, 2012, 57(4): 1098-1101.

DOI：10.1111/j.1556-4029.2012.02095.x

• forensic science
• forensic DNA analysis
• sexual assault
• paternity
• DNA database
• AmpFlSTR (R) SGM Plus (R)
• AmpFlSTR (R) Minifiler (TM)
• PowerPlex (R) 16
• AmpFlSTR (R) YFiler (R)

A sexual assault case resulted in a pregnancy, which was subsequently aborted. The alleged father of the fetus was unknown. Maternal and fetal types were obtained using the 11-locus AmpFlSTR (R) SGM Plus (R) kit. The national DNA database was searched for the paternal obligatory alleles and detected two suspects who could not be excluded as father of the male fetus. Additional typing using the AmpFlSTR (R) Minifiler (TM) kit, containing three additional autosomal loci, was not sufficient to exclude either suspect. Subsequent typing using the PowerPlex (R) 16, containing four additional loci, and Y-Filer (TM) kits resulted in excluding one suspect. Searching a database for paternal obligatory alleles can be fruitful, but is fraught with possible false positive results so that finding a match must be taken as only preliminary evidence.

• 出版日期2012-7