A new preparative method and some chemical properties of 4-R-furazan-3-carboxylic acid amidrazones

作者：Stepanov Andrei I^*; Sannikov Vladimir S; Dashko Dmitry V; Roslyakov Alexey G; Astrat'ev Alexander A; Stepanova Elena V

来源：Chemistry of Heterocyclic Compounds, 2015, 51(4): 350-360.

DOI：10.1007/s10593-015-1707-4

• amidrazone
• furazan
• 1,2,4-oxadiazole
• tetrazole
• 1,2,4-triazine
• 1,2,4-triazole

An alternative method has been developed for the preparation of 4-R-furazan-3-carboxylic acid amidrazones (R = OMe, NH2, substituted amino group) by reductive opening of 1,2,4-oxadiazole ring in 4-R derivatives of (1,2,4-oxadiazol-3-yl)furazans by the action of hydrazine. The starting 1,2,4-oxadiazoles were synthesized from 4-aminofurazan-3-carboxylic acid amidoxime. Some chemical properties of the obtained compounds were studied.

• 出版日期2015-4