An extremely rapid-response fluorescent probe for hydrogen peroxide and its application in living cells

作者：Zhan, Fuxu; Yang, Qian; Wang, Qiufen; Zhang, Qilong; Zhuang, Zhiyuan; Feng, Xue; Zhang, Guangyou; Zheng, Gengxiu^*

来源：RSC Advances, 2016, 6(92): 89940-89943.

DOI：10.1039/c6ra12984f

• OXIDATIVE DNA-DAMAGE
• TURN-ON
• CELLULAR DEFENSES
• PROTEIN OXIDATION
• REACTIVE OXYGEN
• NADPH OXIDASE
• IN-VIVO
• H2O2
• SUPEROXIDE
• ACTIVATION

A turn-on fluorescence probe ACF for rapid detection of H2O2 was constructed. The probe utilized a 2-(azidomethyl) benzoyl group as a new reaction site, which exhibited a rapid response to H2O2 with a 118-fold fluorescence enhancement within 5 min. The biological application of ACF was confirmed by fluorescence imaging H2O2 in living cells.

• 出版日期2016
• 单位济南大学