Postirradiation Klebsiella pneumoniae-Associated Necrotizing Fasciitis in the Western Hemisphere: A Rare but Life-Threatening Clinical Entity

作者：Kelesidis Theodoros^*; Tsiodras Sotirios

来源：American Journal of the Medical Sciences, 2009, 338(3): 217-224.

DOI：10.1097/maj.0b013e3181a393a4

• Necrotizing fasciitis
• Klebsiella pneumoniae
• Radiotherapy
• Soft tissue infection
• Gram negative bacteria

Necrotizing fasciitis (NF) caused by Klebsiella spp. is a unique entity, particularly, in Asia, where virulent strains of Klebsiella predominate. It is now clear that Klebsiella spp. are capable of causing NF either isolated or in the context of disseminated disease. We present a unique case of NF caused by Klebsiella pneumoniae in the Western hemisphere after radiotherapy in a hospitalized patient with significant comorbidities. Physicians should be aware of nosocomially acquired K. pneumoniae fasciitis after radiotherapy in the setting of chronic comorbidities, such as diabetes and malignancy. Early diagnosis, surgical intervention, and appropriate empirical antibiotics are essential for a favorable outcome in such rare but life-threatening cases of NF.

• 出版日期2009-9