A colorimetric and near-infrared fluorescent probe with high sensitivity and selectivity for acid phosphatase and inhibitor screening

作者：Xu, Yongqian^*; Li, Benhao; Xiao, Liangliang; Ouyang, Jia; Sun, Shiguo; Pang, Yi

来源：Chemical communications, 2014, 50(63): 8677-8680.

DOI：10.1039/c3cc49254k

• TURN-ON DETECTION
• ALKALINE-PHOSPHATASE
• PERYLENE PROBE
• PROSTATE-CANCER
• CONJUGATED POLYELECTROLYTE
• ASSAY
• BIOMARKERS
• PROTEIN
• AGGREGATION
• GLUTATHIONE

A dual-channel including a colorimetric and fluorescent probe based on the aggregation-caused quenching (ACQ) and enzymolysis approach has been presented to screen acid phosphatase (ACP) and its inhibitor. Moreover, the ACP activity was determined by real time assay.

• 出版日期2014-8-14
• 单位西北农林科技大学; 陕西师范大学; 西北工业大学