A Receptor for All Occasions

作者:Irvine Darrell J*
来源:Cell, 2016, 164(4): 599-600.
DOI:10.1016/j.cell.2016.01.030

摘要

Cells communicate with their environment, in part, through cell surface receptors. Engineering receptors that both sense arbitrary inputs and provide outputs orthogonal to endogenous signaling pathways has been a challenge. Now, Lim and colleagues report a system based on synthetic Notch receptors that allows independent control of both inputs and outputs in diverse cell types.

  • 出版日期2016-2-11