科研之友
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摘要
Susceptibility to Crohn's disease has been linked to polymorphisms in genes involved in two pathophysiological pathways: autophagy and the recognition of bacterial peptidoglycan by nucleotide oligomerization domain-2 (NOD2), an intracellular receptor. Two studies link these pathways by showing that recognition of bacterial peptidoglycans by NOD2 induces autophagy and bacterial clearance.
- 出版日期2010-1
