A ratiometric fluorescent probe with unexpected high selectivity for ATP and its application in cell imaging

作者:Tang, Jia Liang; Li, Chun Yan*; Li, Yong Fei; Zou, Chun Xiang
来源:Chemical communications, 2014, 50(97): 15411-15414.
DOI:10.1039/c4cc08044k

摘要

Naphthalimide-rhodamine compound (NR) is developed as a ratiometric fluorescent probe for ATP detection based on the FRET mechanism. It shows an unexpected high selectivity for ATP over other anions, especially organic phosphate anions, due to simultaneous interactions of two recognition sites, which benefits fluorescence imaging in living cells.