An Improved Process for Trimethobenzamide Hydrochloride

作者:Neelakandan K*; Manikandan H; Santosha N; Prabhakaran B
来源:Organic Process Research & Development, 2013, 17(7): 981-984.
DOI:10.1021/op400113a

摘要

An improved process for the preparation of trimethobenzamide hydrochloride conforming to regulatory specification is reported. Specifically, a process for the preparation of trimethobenzamide hydrochloride, which is free from the associated impurities that are normally encountered during coupling of 4-(2-dimethylaminoethoxy)benzyl amine with 3,4,5-trimethoxy benzoic acid is described.

  • 出版日期2013-7