科研之友
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摘要
Aim: The ankle-brachial index (ABI) is an easy-to-use, non-invasive and reliable diagnostic tool for assessing peripheral arterial occlusive disease (PAOD). The CHADS(2) (congestive heart failure, hypertension, age. 75 years, diabetes, prior stroke) score is a simple and popular clinical parameter that is used to assess the risk of stroke in patients with atrial fibrillation (AF). Because all five components of the CHADS(2) score are risk factors for PAOD, the score should have a strong correlation with the presence of PAOD. However, there are limited studies regarding the association between the CHADS(2) score and PAOD in patients without AF. Therefore, the aim of the present study was to investigate whether the CHADS(2) score is positively associated with PAOD in patients without AF. %26lt;br%26gt;Methods: A total of 1,320 patients without AF were included in this study. The ABI was measured using an ABI-form device. PAOD was defined as an ABI of %26lt; 0.9 in either leg. %26lt;br%26gt;Results: Among the 1,320 subjects (mean age: 60.3 +/- 13.4 years), the prevalence of an ABI of %26lt; 0.9 was 5.7%. A multivariate analysis showed that an increased age (odds ratio [OR], 1.054; p %26lt; 0.001), decreased estimated glomerular filtration rate (OR, 0.971; p %26lt; 0.001) and increased CHADS(2) score (OR, 1.861; p %26lt; 0.001) were independently associated with an ABI of %26lt; 0.9. %26lt;br%26gt;Conclusions: Our study demonstrated that the CHADS(2) score is significantly associated with an ABI of %26lt; 0.9 in non-AF patients. Further prospective studies are needed to examine the ability of the CHADS(2) score to predict the incidence of PAOD.
- 出版日期2014
