Comparison of health-related quality-of-life outcomes for African-American and Caucasian-American men after radical prostatectomy

作者：Lee Eugene W; Marien Tracy; Laze Juliana; Agalliu Ilir; Lepor Herbert^*

来源：BJU International, 2012, 110(8): 1129-1133.

DOI：10.1111/j.1464-410X.2012.10951.x

• African-American
• erectile dysfunction
• incontinence
• prostate cancer
• prostatectomy
• health-related quality of life

OBJECTIVE
To determine if any differences exist in postoperative health-related quality-of-life (HRQL) outcomes, e. g. erectile function and continence, after radical prostatectomy (RP) in African-American (AA) vs Caucasian-American (CA) men.
PATIENTS AND METHODS
Between October 2000 and July 2008, 1338 CA and 56 AA men underwent open RP by a single surgeon and signed informed consent to participate in a prospective longitudinal outcomes study.
The American Urological Association Symptom Score (AUA-SS) and University of California, Los Angeles, Prostate Cancer Index (UCLA-PCI) and a global assessment of satisfaction were self-administered at baseline and after RP 24 months.
Urinary, sexual, and satisfaction outcomes were compared at 24 months.
RESULTS
AA men had significantly higher rates of hypertension and diabetes.
There were no other significant baseline differences in age, co-morbidities, body mass index, phosphodiesterase type 5 inhibitor use, preoperative prostate-specific antigen level, AUA-SS, and UCLA-PCI scores.
There were no differences in the percentage of men undergoing nerve-sparing procedures, estimated blood loss, transfusion rates, or complication rates between the groups.
At 24 months after RP the mean UCLA-PCI urinary and sexual function and bother scores and global satisfaction scores were similar between the groups.
CONCLUSION
AA and CA men experience no significant differences in urinary and sexual HRQL or overall satisfaction after open RP when performed by a single experienced surgeon.

• 出版日期2012-10