Acute Lymphoid Leukemia After Anti-TNF-alpha Treatment: A Case Report and Review of the Literature

作者:Gediz Ozdemirkiran Fusun*; Payzin Bahriye Kadriye; Coban Eyup; Bayram Korhan Baris; Kucukzeybek Betul
来源:Archives of Rheumatology, 2015, 30(4): 349-352.
DOI:10.5606/ArchRheumatol.2015.5669

摘要

The efficacy and safety of anti-tumor necrosis factor-alpha drugs have been shown in active ankylosing spondylitis cases that are resistant to traditional disease-modifying antirheumatic drugs. However, it is well known that these drugs may cause some complications as reactivation of tuberculosis and various hematologic malignancies. In this article, we report a 40-year-old male patient with ankylosing spondylitis who developed Philadelphia chromosome-positive acute lymphoid leukemia after treatment with tumor necrosis factor-alpha inhibitors.

  • 出版日期2015