An efficient microwave-assisted synthesis furo[3,4-b][4,7]phenanthroline and indeno[2,1-b][4,7]phenanthroline derivatives in water

作者:Shi Feng; Zhou Dianxiang; Tu Shujiang*; Shao Qingqing; Li Chunmei; Cao Longji
来源:Journal of Heterocyclic Chemistry, 2008, 45(4): 1065-1070.
DOI:10.1002/jhet.5570450418

摘要

A series of furo[3,4-b][4,7]phenanthroline and indeno[2,1-b][4,7]phenanthroline derivatives were synthesized via a three-component reaction of aromatic aldehydes, 6-aminoquinoline and either tetronic acid or 1,3-indanedione in water, under microwave irradiation without use of any catalyst. This green procedure offers several advantages including operational simplicity, clean reaction, and increased safety for small-scale high-speed synthesis.