Actin nucleation: Putting the brakes on Arp2/3

作者:Qualmann Britta*; Kessels Michael M
来源:Current Biology, 2008, 18(10): R420-R423.
DOI:10.1016/j.cub.2008.04.014

摘要

The Arp2/3 complex is a powerful nucleator of actin filaments when activated. A recent study has now revealed that this complex is not only subject to positive control but that there also exists a brake on its activity. This brake can suppress both the basal activity of the Arp2/3 complex as well as its activation by nucleation-promoting factors.

  • 出版日期2008-5-20