Discordance in Femoral Neck Bone Density in Subjects With Unilateral Hip Osteoarthritis

作者：Glowacki Julie; Tuteja Meenu; Hurwitz Shelley; Thornhill Thomas S; LeBoff Meryl S^*

来源：Journal of Clinical Densitometry, 2010, 13(1): 24-28.

DOI：10.1016/j.jocd.2009.09.007

• Bilateral BMD
• hip
• osteoarthritis

Osteoarthritis (OA) is a common disease that increases in incidence with age and currently affects an estimated 27 million Americans. To determine whether site-specific hip bone mineral density (BMD) measures are confounded by the presence of OA, we measured bilateral hip BMD by dual X-ray absorptiometry in 34 subjects (19 women and 15 men) scheduled for hip replacement for confirmed advanced unilateral hip OA. The femoral neck (FN) BMD (p = 0.035) and T-score (p = 0.017) for the hip with OA was higher than those of the contralateral hip. There was a difference in osteoporosis classification depending on which hip was considered: for 11 of the 34 subjects (32%), the FN T-score was normal for OA hip, but the contralateral hip was classified as osteopenic (T-score between -1.0 and -2.5). For 1 subject, the FN T-score was normal for OA hip, but the contralateral hip was classified as osteoporotic (T-score below -2.5). Discordance was also present for trochanter values and not for total hip values. These data indicate that advanced hip OA can be associated with a higher bone density at the FN and trochanter but not at total hip and that the discrepancy between hips at the FN may have an impact on patient treatment decisions.

• 出版日期2010-3