ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins

作者：Pineda Sandy S.^*; Chaumeil Pierre-Alain; Kunert Anne; Kaas Quentin; Thang Mikew. C.; Le Lien; Nuhn Michael; Herzig Volker; Saez Natalie J.; Cristofori-Armstrong Ben; Anangi Raveendra; Senff Sebastian; Gorse Dominique; King Glenn F.^*

来源：Bioinformatics, 2018, 34(6): 1074-1076.

DOI：10.1093/bioinformatics/btx661

ArachnoServer is a manually curated database that consolidates information on the sequence, structure, function and pharmacology of spider-venom toxins. Although spider venoms are complex chemical arsenals, the primary constituents are small disulfide-bridged peptides that target neuronal ion channels and receptors. Due to their high potency and selectivity, these peptides have been developed as pharmacological tools, bioinsecticides and drug leads. A new version of ArachnoServer (v3.0) has been developed that includes a bioinformatics pipeline for automated detection and analysis of peptide toxin transcripts in assembled venom-gland transcriptomes. ArachnoServer v3.0 was updated with the latest sequence, structure and functional data, the search-by-mass feature has been enhanced, and toxin cards provide additional information about eachmature toxin.

• 出版日期2018-3-15