A facile and simple polyaniline-poly(ethylene oxide) based glucose biosensor

作者：Hansen Betina^*; Hocevar Marcele A; Ferreira Carlos A

来源：Synthetic Metals, 2016, 222: 224-231.

DOI：10.1016/j.synthmet.2016.10.028

• Polyaniline
• Poly(ethylene oxide)
• Nanocomposite
• Biosensor
• Glucose oxidase

In this work, the fabrication and performance of a simple and efficient glucose biosensor based on chemically synthesized polyaniline-poly(ethylene oxide) nanocomposite (PAni-PEO) have been demonstrated. The nanocomposite was synthesized through rapid-mixing polymerization and characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FT-IR). The nanocomposite and glucose oxidase (GOx) solutions were placed on a platinum electrode by drop-casting, to produce a glucose biosensor that was characterized by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and chronoamperometry. Under optimal conditions, the biosensor showed a linear range from 1 to 10 mM (R-2 = 0.990) with a high sensitivityof 16.04 mu AmM-1 cm(-2) and a detection limit of 0.82 mM. The interference from ascorbic acid (AA) and uric acid (UA) was also investigated. The results indicated that the biosensor exhibited a satisfactory linear range, sensibility, and selectivity for use as a glucose biosensor, considering the normal range of approximately 4-6 mM of glucose concentration in human blood.

• 出版日期2016-12