Using neuroimaging to help predict the onset of psychosis

作者：Gifford George; Crossley Nicolas; Fusar Poli Paolo; Schnack Hugo G; Kahn Rene S; Koutsouleris Nikolaos; Cannon Tyrone D; McGuire Philip

来源：NeuroImage, 2017, 145: 209-217.

DOI：10.1016/j.neuroimage.2016.03.075

• Psychosis prediction
• Ultra high-risk of psychosis
• Machine learning
• Support vector machines
• Multimodal neuroimaging
• Multicentre neuroimaging studies
• Graph analysis

The aim of this review is to assess the potential for neuroimaging measures to facilitate prediction of the onset of psychosis. Research in this field has mainly involved people at 'ultra-high risk' (UHR) of psychosis, who have a very high risk of developing a psychotic disorder within a few years of presentation to mental health services. The review details the key findings and developments in this area to date and examines the methodological and logistical challenges associated with making predictions in an individual subject in a clinical setting.

• 出版日期2017-1-15