Lymphocytic Hypophysitis Accompanied by Aseptic Meningitis Mimics Subacute Meningoencephalitis

作者：Suzuki Keisuke^*; Izawa Naoki; Nakamura Toshiki; Hashimoto Kenichi; Ouchi Keita; Sakuta Hideki; Asakawa Yohei; Numao Ayaka; Hirata Koichi

来源：Internal Medicine, 2011, 50(18): 2025-2030.

DOI：10.2169/internalmedicine.50.5386

• lymphocytic hypophysitis
• aseptic meningitis
• tuberculous meningitis
• hypopituitarism
• diabetes insipidus

A 66-year-old man was admitted to our hospital with muscle pain, fatigue and appetite loss that had lasted for a month. The patient was somnolent and had nuchal stiffness with a high fever. Cerebrospinal fluid (CSF) tests demonstrated lymphocytic pleocytosis with a decreased CSF-blood glucose ratio. The tests for tuberculous, fungal and carcinomatous meningitis and herpetic meningoencephalitis were negative. Endocrinological exams showed hypopituitarism and diabetes insipidus. A pituitary MRI showed an enlargement of the pituitary stalk. A diagnosis of lymphocytic hypophysitis with aseptic meningitis was made after the exclusion of secondary hypophysitis. Lymphocytic hypophysitis with aseptic meningitis can mimic subacute meningoencephalitis.

• 出版日期2011