摘要

Purpose: To investigate the relationship between axial length (AL) increase and baseline spherical equivalent refractive errors (SER) in myopic children wearing orthokeratology contact lenses (OK). @@@ Methods: One hundred fifteen Chinese (115 right eyes) children wearing OK were enrolled in this cohort study. Gender, age, baseline SER, corneal power, corneal astigmatism, and AL at baseline and 2 years after wearing OK were collected. Univariate analysis and trend test were used to estimate the relationship between change in AL and baseline SER. @@@ Results: After univariate analysis, a statistically significant relationship was found between change in AL and baseline SER (beta = 0.061, 95% CI: 0.015-0.111, P = 0.015). In the trend test, after adjusting for potential confounders, higher SER was associated with smaller increases in AL (P trend = 0.041). @@@ Conclusions: The SER at baseline was associated with AL growth in myopic children wearing OK. The higher SER was associated with slower AL growth and control the development of myopia.