A Favorable Response to Levetiracetam in a Patient with Metastatic Adenoid Cystic Carcinoma

作者:Sakata Shinya; Saeki Sho*; Terasaki Yasuhiro; Natori Yoshihiro; Fujii Kazuhiko
来源:Internal Medicine, 2018, 57(5): 721-724.
DOI:10.2169/internalmedicine.9300-17

摘要

Adenoid cystic carcinoma (ACC) is a rare cancer, and there are no standard-of-care treatments for patients with metastatic ACC. We herein report a patient with lung metastasis of ACC who achieved a favorable response to levetiracetam. A 52-year-old Japanese man was admitted to our hospital because of multiple lung metastases of ACC. We performed first-line chemotherapy with cisplatin plus gemcitabine, and subsequently oral S-1 as second-line chemotherapy, which resulted in disease progression. The patient developed symptomatic epilepsy and received levetiracetam (250 mg twice daily). At five months after the initiation of levetiracetam, chest computed tomography showed regression of the metastatic lung lesions.

  • 出版日期2018