Preparation and characterization of Rana chensinensis skin extract/poly(epsilon-caprolactone) electrospun membranes as antibacterial fibrous mats

作者：Zhang Mei; Xu Wen Yu; Wang Jia Mian; Luan Jia Shuang; Dong He Nan; Zhang Yu Jing; Li Xue Qi; Sun Da Hui^*

来源：Journal of Applied Polymer Science, 2015, 132(23): 42030.

DOI：10.1002/app.42030

• biomaterials
• electrospinning
• fibers
• membranes
• packaging

In this study, membranes composed of Rana chensinensis skin extracts (RCSEs) and poly(epsilon-caprolactone) (PCL) were fabricated by an electrospinning technique. The RCSEs were prepared by the extraction of R. chensinensis skin with acetic acid solution, and the electrospun membranes were prepared by the mixture of RCSEs and PCL in 1,1,1,3,3,3-hexafluoro-2-propanol before electrospinning. The membranes were characterized by scanning electron microscopy and Fourier transform infrared spectroscopy and were subjected to mechanical tests (tensile and nanoindentation) and antibacterial evaluation. The results indicate that the surface roughness of the fibers clearly decreased with the increase in the amount of PCL in the membranes. The mechanical test indicated that PCL played a dominant role in the mechanical strength of the RCSE/PCL electrospun membranes. As a potential bactericidal packaging material for practical applications, the antibacterial activity results indicate that the membranes had antibacterial effects against Staphylococcus aureus and Escherichia coli.

• 出版日期2015-6-15
• 单位吉林大学