Acid and base degraded products of ketorolac

作者：Salaris Margherita; Nieddu Maria; Rubattu Nicola; Testa Cecilia; Luongo Elvira; Rimoli Maria Grazia; Boatto Gianpiero^*

来源：Journal of Pharmaceutical and Biomedical Analysis, 2010, 52(2): 320-322.

DOI：10.1016/j.jpba.2010.01.031

• Ketorolac
• Acid and base stability
• Degradation products
• LC-MS

The stability of ketorolac tromethamine was investigated in acid (0.5M HCl) and alkaline conditions (0.5 M NaOH), using the same procedure reported by Devarajan et al. [2]. The acid and base degradation products were identified by liquid chromatography-mass spectrometry (LC-MS).

• 出版日期2010-6-5