A novel symmetric sulfur-containing biscembranoid from the Formosan soft coral Sinularia flexibilis

作者：Chen, Bo Wei; Chao, Chih Hua; Su, Jui Hsin; Huang, Chiung Yao; Dai, Chang Feng; Wen, Zhi Hong; Sheu, Jyh Horng^*

来源：Tetrahedron Letters, 2010, 51(44): 5764-5766.

DOI：10.1016/j.tetlet.2010.08.027

• Soft coral
• Sinularia flexibilis
• Thioflexibilolide A
• Anti-inflammatory activity
• Neuroprotective activity

A structurally unique symmetric sulfur-containing biscembranoid, namely, thioflexibilolide A (1), was isolated from the soft coral Sinularia flexibilis. The structure was determined by extensive spectroscopic analyses. Compound 1 has been found to possess significant anti-inflammatory and neuroprotective activities.

• 出版日期2010-11-3
• 单位中山大学