Antioxidant activities and UV-protective properties of melanin from the berry of Cinnamomum burmannii and Osmanthus fragrans

作者：Huang, Shiwen; Pan, Yingming; Gan, Dianhua; Ouyang, Xilin; Tang, Shaoqing; Ekunwe, Stephen I. N.; Wang, Hengshan^*

来源：Medicinal Chemistry Research, 2011, 20(4): 475-481.

DOI：10.1007/s00044-010-9341-2

• Melanin
• Total antioxidant activities
• Sun protection factor
• Cinnamomum burmannii
• Osmanthus fragrans

Cinnamomum burmannii and Osmanthus fragrans are traditional and famous ornamental plants. Melanin-like pigment derived from the berry of C. burmannii (CBM) and O. fragrans (OFM) was isolated with total yield of 0.34 g/100 g and 0.12 g/100 g (wet weight basis), respectively. The color values of CBM and OFM were E (1cm) (1%) 205 nm = 60.24 and E (1cm) (1%) 278 nm = 65.21, respectively. CBM and OFM were found to be scarcely soluble in water and most common organic solvents, but soluble in alkaline aqueous and slightly soluble in DMSO. Both of them exhibited significant antioxidant activities superior to BHT. The reducing power/abilities of CBM and OFM increased with the amount of sample and decreased in the order of OFM > CBM > BHT. The metal chelating activities of CBM and OFM were concentration-dependent. Moreover, the metal scavenging effects of the samples decreased in the order of BHT > CBM > OFM. Results from the sun protection factor (SPF) in vitro determination of melanin-bearing gel formulations indicated that the SPF value of every formulation increased with amount of melanin, which suggested the presence of additional compounds with sunscreen activity in the melanin extract; the synergistic effect of CBM on the SPF of gel formulations was greater than that of OFM.

• 出版日期2011-5
• 单位广西师范大学