Dual-signaling fluorescent chemosensor based on bisthiazole derivatives

作者：Helal Aasif; Lee Sang Hoon; Kim Sung Hong; Kim Hong Seok^*

来源：Tetrahedron Letters, 2010, 51(27): 3531-3535.

DOI：10.1016/j.tetlet.2010.04.126

• Bisthiazole
• Fluorescence
• ESIPT
• Ratiometric sensing
• Quenching

A new bisthiazole chemosensor (3) with phenolic substituents at the position 2 of the thiazole rings was prepared. The chemosensor 3 acts as a potential dual-function fluorescence chemosensor with Cu(2+) and Zn(2+) ions causing complete quenching and ratiometric change of fluorescence, respectively. The mechanism of fluorescence was based on the cation-induced inhibition of excited-state intramolecular proton transfer (ESIPT).

• 出版日期2010-7-7