Accuracy of Automated Attenuation-Based 3-Dimensional Segmentation in the Analysis of Left Ventricular Function Compared with Magnetic Resonance Imaging

作者：Brodoefel Harald^*; Tsiflikas Ilias; Kramer Ulrich; Lang Nina; Reimann Anja; Burgstahler Christoph; Claussen Claus D; Heuschmid Martin

来源：Texas Heart Institute Journal, 2012, 39(1): 36-43.

• Cardiovascular magnetic resonance
• hypertrophy, left ventricular/diagnosis
• magnetic resonance angiography
• magnetic resonance imaging, cine
• models, cardiovascular
• pattern recognition, automated/methods
• prospective studies
• radiographic image enhancement/methods
• radiographic image interpretation, computer-assisted
• tomography, x-ray computed
• ventricular dysfunction, left/diagnosis/radiography

We evaluated attenuation-based 3-dimensional segmentation for the analysis of left ventricular function, using as our standard of reference magnetic resonance imaging and dual-source computed tomography with traditional short-axis planimetry. %26lt;br%26gt;Twenty patients with known or suspected coronary artery disease were examined prospectively. In all magnetic resonance and computed tomographic datasets, global functional values were determined by 2-dimensional planimetry. Computed tomographic scans were further evaluated by automated 3-dimensional segmentation, and the results were compared by Pearson correlation and Bland-Altman analysis. %26lt;br%26gt;Agreement between magnetic resonance imaging and dual-source computed tomographic 2-dimensional planimetry was good for all values (end-diastolic volume, bias= -4.2 r=0.99; end-systolic volume, bias= -1.7 r=0.99, stroke-volume, bias= -2.4, r=0.98; ejection fraction, bias=0.26, r=0.94; and myocardial mass, bias= 2.5, r=0.90). By contrast, dual-source computed tomographic 3-dimensional segmentation overestimated end-diastolic volume (bias= -19.1, P %26lt;0.001), stroke-volume (bias= -16.9, P %26lt;0.001), and myocardial mass (bias= -34.4, P %26lt;0.001). Moreover, correlation with magnetic resonance imaging proved disappointing for ejection fraction (r=0.72). Results were similar in a direct comparison between dual-source computed tomographic 2-dimensional planimetry and 3-dimensional segmentation (end-diastolic volume, bias= -14.9, r=0.94; end-systolic volume, bias= -0.5, r=0.90; stroke volume, bias= -14.5, r=0.83; ejection fraction, bias= -2.8, r=0.74; and myocardial mass, bias= -36.8, r=0.79). %26lt;br%26gt;Due to significant overestimation of volumes and poor correlation of ejection fraction with cine magnetic resonance imaging results, attenuation-based 3-dimensional segmentation compares unfavorably with traditional planimetry. Hence this method should be used with caution, and its time benefits should be weighed against its imprecision of functional analysis. (Tex Heart Inst J 2012;39(1):36-43)

• 出版日期2012-2