Al(OH)(3) facilitated synthesis of water-soluble, magnetic, radiolabelled and fluorescent hydroxyapatite nanoparticles

作者:Cui X; Green M A*; Blower P J; Zhou D; Yan Y; Zhang W; Djanashvili K; Mathe D; Veres D S; Szigeti K
来源:Chemical communications, 2015, 51(45): 9332-9335.
DOI:10.1039/c5cc02259b

摘要

Magnetic and fluorescent hydroxyapatite nanoparticles were synthesised using Al(OH)(3)-stabilised MnFe2O4 or Fe3O4 nanoparticles as precursors. They were readily and efficiently radiolabelled with F-18. Bisphosphonate polyethylene glycol polymers were utilised to endow the nanoparticles with excellent colloidal stability in water and to incorporate cyclam for high affinity labelling with Cu-64.

  • 出版日期2015