Mathematical modeling of biomass and alpha-amylase production kinetics by Bacillus sp in solid-state fermentation based on solid dry weight variation

作者：Hashemi M; Mousavi S M; Razavi S H^*; Shojaosadati S A

来源：Biochemical Engineering Journal, 2011, 53(2): 159-164.

DOI：10.1016/j.bej.2010.09.017

• Modeling
• Biomass
• alpha-Amylase production
• Solid-state fermentation
• Dry weight

Modeling the different phases of the bacterial growth curve and the production of alpha-amylase by Bacillus sp. KR-8104 in a solid-state fermentation process based on variation in dry weight was the aim of this study. The result showed that the growth of bacterial cells and the production of alpha-amylase on a wheat bran substrate could be expressed by simple models incorporating the mathematical definition of each phase and the variation in dry substrate weight over the incubation time. Experimental data collected from a series of batch fermentations were used to validate the models proposed. In both cases, the model simulation matched well with the experimental observations, which made it possible to conclude that these models can be successfully employed for the development of growth and alpha-amylase production in solid-state fermentation processes.

• 出版日期2011-1-15