Development and Validation of the Dyspnea Index (DI): A Severity Index for Upper Airway-Related Dyspnea

作者：Gartner Schmidt Jackie L^*; Shembel Adrianna C; Zullo Thomas G; Rosen Clark A

来源：Journal of Voice, 2014, 28(6): 775-782.

DOI：10.1016/j.jvoice.2013.12.017

• Dyspnea
• Paradoxical Vocal Fold Motion Disorder (PVFMD)
• Vocal Cord DysVCD)
• Laryngeal stenosis
• Glottal stenosis
• Shortness of breath
• Questionnaire
• Symptom severity
• Outcomes

Objectives. To (1) develop and validate the Dyspnea Index (DI); (2) quantify severity of symptoms in upper airway dyspnea; and (3) validate the DI as an outcome measure.
Study Design. Survey development and validation.
Methods. Three hundred sixty-nine participants were recruited for different phases of the study. Two hundred participants with chief complaints of dyspnea were given a 41-item questionnaire addressing common symptoms of dyspnea related to the upper airway. The questions were then reduced based on principal component analysis (PCA) and internal consistency resulting in a 10-item questionnaire. Cognitive interviews were conducted with 15 participants. Test-retest reliability and discriminant validity were measured from 51 participants. The DI was further validated by administering the index to 57 healthy controls (HC). Validation of the DI as a treatment outcome tool occurred with 46 participants' pre-and post-treatment scores.
Results. PCA revealed that only a single factor was being measured in both the original 41- and 10-item questionnaires. Additional cognitive interviewing suggested that no modification was needed to the DI. Test-retest reliability was r = 0.83. Discriminant validity was r = 0.62. The Mann-Whitney test demonstrated significant differences between healthy/symptomatic participants. Scores from the HC cohort resulted in a mean of 3.12 (SEM = 0.484; SD = 3.65) for the normative values.
Conclusions. The DI is an effective and efficient instrument to quantify patients' symptoms of upper airway dyspnea. It is a statistically robust index, with significant reliability and validity, and can be dependably used as a treatment outcome measure.

• 出版日期2014-11