Macular Telangiectasia Type 2 Without Clinically Detectable Vasculopathy

作者：Gillies Mark C^*; Mehta Hemal; Bird Alan C

来源：JAMA Ophthalmology, 2015, 133(8): 951-954.

DOI：10.1001/jamaophthalmol.2015.1796

IMPORTANCE Macular telangiectasia type 2 is a bilateral disease with characteristic alterations of the macular capillary network and neural atrophy. Vascular and neurodegenerative hypotheses have been proposed to explain these clinical findings, but many questions regarding the pathogenesis remain.
OBSERVATIONS We report the case of a 69-year-old woman with macular telangiectasia type 2 in whom multimodal fundus imaging identified neuronal features without clinically detectable vasculopathy.
CONCLUSIONS AND RELEVANCE We hypothesize that parallel neuronal and vascular pathogenic pathways secondary to Muller cell dysfunction, the cause of which remains obscure, explain the clinical features of this case of macular telangiectasia type 2.

• 出版日期2015-8