alpha-fetoprotein-producing endometrial adenocarcinoma without an obvious hepatoid component

作者：Kodama Junichi^*; Seki Noriko; Yanai Hiroyuki; Kusumoto Tomoyuki; Nakamura Keiichiro; Hongo Atsushi; Hiramatsu Yuji

来源：Oncology Letters, 2010, 1(2): 243-245.

DOI：10.3892/ol_00000043

• endometrial adenocarcinoma
• alpha-fetoprotein
• hepatoid

Endometrial carcinomas producing alpha-fetoprotein (AFP) are extremely rare We report a case of AFP-producing, Grade 2 endometrioid adenocarcinoma without an obvious hepatoid component A 59-year-old multiparous woman presented with abdominal swelling The serum level of AFP was 1292 8 ng/ml Magnetic resonance images of the pelvis showed a markedly enlarged uterus, with a tumor growing exophytically within the endometrial cavity Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed The histopathological examination demonstrated a Stage IIA, Grade 2 endometrioid adenocarcinoma without an obvious hepatoid component The endometrioid adenocarcinoma cells were partly positive for AFP immunoreactivity The patient received adjuvant chemotherapy and was disease-free 60 months after the operation This case confirms the existence of AFP-producing endometnoid adenocarcinomas without hepatoid features

• 出版日期2010-4