Monitoring 3D dose distributions in proton therapy by reconstruction using an iterative method

作者：Kim Young Hak; Yoon Changyeon; Lee Wonho^*

来源：Applied Radiation and Isotopes, 2016, 114: 33-39.

DOI：10.1016/j.apradiso.2016.05.005

• Proton therapy
• Bragg peak
• Prompt gamma-Rays
• Single-Photon Emission Computed Tomography (SPECT)
• Iterative reconstruction method

The Bragg peak of protons can be determined by measuring prompt gamma-rays. In this study, prompt gamma-rays detected by single-photon emission computed tomography with a geometrically optimized collimation system were reconstructed by an iterative method. The falloff position by iterative method (52.48 mm) was most similar to the Bragg peak (52 mm) of an 80 MeV proton compared with those of back-projection (54.11 mm) and filtered back-projection (54.91 mm) methods. Iterative method also showed better image performance than other methods.

• 出版日期2016-8