摘要

A microchip with eight Cr-Au electrodes was elaborated, designed, and fabricated for the microfluidic detection of apoptotic cells. The eight Cr-Au electrodes consist of four pairs of electrodes located opposite to each other and form a ring. The inner diameter of the ring section for microfluidic droplet placement was 400 mu m. Then a rotating electric field is produced by the eight-electrode structure. The electric field at the center of the microchip circle was nearly consistent and stable enough to ensure that almost all the tested biological particles will have a consistent rotation speed. The proposed microfluidic biochip with eight Cr-Au electrodes is recommended for the cell screening and rapid clinical detection of damaged cells at the middle and late stages of apoptosis.