Activator-free and one-pot C-allylation by simple palladium catalyst in water

作者：Shue Yi Jen; Yang Shyh Chyun^*

来源：Tetrahedron Letters, 2012, 53(11): 1380-1384.

DOI：10.1016/j.tetlet.2012.01.022

• Activator-free
• Allylic alcohols
• Palladium
• Water
• Cyclic 1,3-diones

For atom economic and green chemistry concepts, we develop a reaction that involves one-pot and one step to construct the C-C bond without the help of any activating reagents for allylic alcohols in water. The palladium-catalyzed allylation of cyclic 1,3-diones using allylic alcohols directly gave the corresponding allylated products in 8-99% yields.

• 出版日期2012-3-14