摘要

A very short and efficient stereoselective total synthesis of a macrocyclic ketone, 11 beta-methoxycurvularin was achieved by employing the Sharpless asymmetric epoxidation, formation of propargyl alcohols from an epoxy-chloride, and intramolecular Friedel-Crafts acylation as the key steps.

  • 出版日期2014