A new cerebroside from Gynura divaricata

作者：Chen, Lei; Wang, Jin-Jiang; Zhang, Guo-Gang; Song, Hong-Tao^*; Qin, Lu-Ping

来源：Natural Product Research, 2009, 23(14): 1330-1336.

DOI：10.1080/14786410902836677

• Gynura divaricata
• compositae
• cerebrosides
• sphingolipids
• chemical constituents

A new cerebroside (1) was isolated from the aerial parts of Gynura divaricata DC., along with five known compounds: kaempferol (2), kaempferol 3-O-glucoside (3), kaempferol 3-O-rhamnosyl(1 6)glucoside (4), -sitosteryl glucoside-6'-O-heptadecoicate (5) and 2-(1', 2', 3', 4'-tetrahydroxybutyl)-6-(2'', 3'', 4''-trihydroxybutyl)-pyrazine (6), which are isolated for the first time from this species. The structure of 1 was determined to be 1-O--D-glucopyranosyl-(2S, 3S, 4R, 10Z)-2-[(2'R)-2'-hydroxylignocenoyl-amino]-10-octadecene-1,3,4-triol on the basis of chemical and spectroscopic evidence.

• 出版日期2009
• 单位沈阳药科大学; 中国人民解放军南京军区福州总医院; 中国人民解放军第二军医大学