Development and characterization of multi-element doped hydroxyapatite bioceramic coatings on metallic implants for orthopedic applications

作者：Furko Monika^*; Havasi Viktor; Konya Zoltan; Gruenewald Alina; Detsch Rainer; Boccaccini Aldo R; Balazsi Csaba

来源：Boletin de la Sociedad Espanola de Ceramica y Vidrio, 2018, 57(2): 55-65.

DOI：10.1016/j.bsecv.2017.09.003

• Coatings
• Microstructure
• Corrosion
• Bioceramics

Multi-element modified bioactive hydroxyapatite bioceramic (mHAp) coatings were successfully developed onto surgical grade titanium alloy material (Ti6Al4V). The coatings were prepared by pulse current deposition from electrolyte containing adequate amounts of calcium nitrate and ammonium dihydrogen phosphate at 70 C. The pure HAp layer was doped and co-deposited with Ag, Zn, Mg, Sr ions. The biocompatible properties of layers were investigated by seeding osteoblast-like MG-63 cells onto the samples' surface. The biocompatible measurements revealed enhanced bioactivity of modified HAp compared to uncoated implant materials and pure bioceramic coating. The morphology and structure of coatings and cells were characterized by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX) as well as FT-IR and XRD measurements. The biodegradable properties of samples were investigated by electrochemical potentiodynamic measurements.

• 出版日期2018-4