Analysis of therapeutic effectiveness attained through generation of three alpha particles in proton-boron fusion reaction based on Monte Carlo simulation code

作者：Kim Sunmi; Yoon Do Kun^*; Shin Han Back; Kim Moo Sub; Suh Tae Suk^*

来源：Journal of Radioanalytical and Nuclear Chemistry, 2018, 316(3): 1059-1065.

DOI：10.1007/s10967-018-5813-5

• Alpha particle
• Proton
• Boron
• Proton-boron fusion reaction
• Monte Carlo simulation

This study analyzed the effectiveness attained through generation of three alpha particles in proton-boron fusion therapy (PBFT) based on a Monte Carlo simulation. PBFT is based on a fusion reaction between protons and boron. Three alpha particles are emitted from this reaction. The three alpha particles cause greater damage to tumor cells than the single alpha particle produced in the boron neutron capture reaction or conventional therapy. In addition, the intrinsic proton dose pattern follows Bragg-peak curve. We confirmed an energy deposition by the alpha particle and verified the therapeutic effect of the PBFT.

• 出版日期2018-6