Ascites and malnutrition are predictive factors for incomplete cytoreductive surgery for peritoneal carcinomatosis from gastric cancer

作者：Benizri Emmanuel I; Bereder Jean Marc^*; Rahili Amine; Bernard Jean Louis; Benchimol Daniel

来源：American Journal of Surgery, 2013, 205(6): 668-673.

DOI：10.1016/j.amjsurg.2012.06.009

• Gastric cancer
• Peritoneal carcinomatosis
• Cytoreductive surgery
• Intraperitoneal chemotherapy

BACKGROUND: Prognosis in peritoneal carcinomatosis from gastric cancer has improved with cytoreductive surgery (CS) and hyperthermic intraperitoneal chemotherapy. The aim of this study was to identify predictive factors for incomplete CS. %26lt;br%26gt;METHODS: Forty-five patients undergoing laparotomy for gastric cancer with peritoneal carcinomatosis were prospectively included from January 2000 to December 2010. In case of optimal CS, patients (n = 14) received hyperthermic intraperitoneal chemotherapy. Otherwise, the laparotomy was closed or a palliative procedure was performed if necessary. All preoperative data were compared between the 2 groups. %26lt;br%26gt;RESULTS: Ascites (hazard ratio, .09; 95% confidence interval, .010-.48; P = .0103) and nutritional status evaluated by the prognostic nutrition index (hazard ratio, .11; 95% confidence interval, .0019-.54; P = .027) were independent predictive factors for incomplete CS. %26lt;br%26gt;CONCLUSIONS: The selection of patients for CS plus hyperthermic intraperitoneal chemotherapy should include the assessment of nutritional status and the detection of an ascites.

• 出版日期2013-6