Diisopropylamine as a single catalyst in the synthesis of aryl disulfides

作者：Kucinski Krzysztof; Hreczycho Grzegorz

来源：Green Processing and Synthesis, 2018, 7(1): 12-15.

DOI：10.1515/gps-2016-0205

<jats:title>Abstract</jats:title>
<jats:p>The search for less time-consuming and inexpensive methods for the synthesis of disulfides continues to be a hot subject of research. Herein, we report that diisopropylamine (<jats:italic>i</jats:italic>Pr<jats:sub>2</jats:sub>NH) can act as a very effective catalyst for this process. The oxidative coupling of aryl thiols was carried out in the presence of catalytic amount of <jats:italic>i</jats:italic>Pr<jats:sub>2</jats:sub>NH in air (room temperature) in acetonitrile, without metal catalyst, additives, or external activators. This procedure opens a low-cost, green, and industrially applicable synthetic pathway to obtain aryl disulfides.</jats:p>

• 出版日期2018-2