Novel benzofuran constituent from the husk of Carya cathayensis Sarg.

作者：Zhang, Shao-Yong; Chen, An-Liang^*; Li, Qiao

来源：Phytochemistry Letters, 2012, 5(3): 473-475.

DOI：10.1016/j.phytol.2012.04.008

• Carya cathayensis Sarg. (CCS)
• Antifungal constituent
• Cathayenone A
• Inhibition rates

In an attempt to find the effective botanical fungicide, investigations were conducted on the husk of Carya cathayensis Sarg. (CCS). The results suggested that the crude extracts from the husk of CCS have obvious germicidal effects on the pathogenic fungi, while screening for new antifungal agents from the husk of C. cathayensis Sarg., a novel benzofuran-type compound, cathayenone A, was obtained. Its structure was elucidated by 1-D and 2-D NMR and MS data analyses. The inhibition rates of 0.1 mg/mL of cathayenone A against the spore germination of Exserohilum turcicum and Pyricularia oryzae were 95.8% and 86.7%, respectively, which showed better antifungal activity than tebuconazole fungicide. Therefore, cathayenone A has the potential to be a fungicide.

• 出版日期2012-9
• 单位浙江农林大学