A new complex triterpenoid saponin from Calliandra pulcherrima with haemolytic activity and adjuvant effect

作者：da Silva Bernadete Pereira; Parente Jose Paz^*

来源：Phytochemistry Letters, 2013, 6(4): 633-639.

DOI：10.1016/j.phytol.2013.08.009

• Calliandra pulcherrima
• Leguminosae
• Complex triterpenoid saponin
• Haemolytic activity
• Adjuvant effect

A new complex triterpenoid saponin was isolated from the leaves of Calliandra pulcherrima by using chromatographic methods. On the basis of chemical evidence, spectroscopic analyses and comparison of known compounds its structure was established as 3-[(O-alpha-L-arabinopyranosyl-(1 -%26gt; 2)-O-alpha-L-arabinopyranosyl-(1 -%26gt; 6)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)oxy]-(3 beta)-olean-12-en-28-oic acid O-beta-D-xylopyranosyl-(1 -%26gt; 3)-O-beta-D-xylopyranosyl-(1 -%26gt; 4)-O-[(beta-D-glucopyranosyl-(1 -%26gt; 3)]-O-6-deoxy-alpha-L-mannopyranosyl-(1 -%26gt; 2)-6-O-[(2E,6S)-6-[[2-O-[(2E,6S)-6-[[6-deoxy-2-O-[(2E,6S)-2,6-dimethyl- 1-oxo-6-(beta-D-xylopyranosyloxy)-2,7-octadienyl]-beta-D-glucopyranosyl]oxy]-2,6-dimethyl-1-oxo-2,7-octadienyl]-beta-D-xylopyranosyl]oxy]-2,6-dimethyl-1-oxo-2,7-octadienyl]-beta-D-glucopyranosyl ester (1). The haemolytic activity of the saponin was evaluated using in vitro assays, and its adju

• 出版日期2013-11