Unicentric, Multifocal Castleman Disease of the Mediastinum Associated With Cerebellitis

作者:Hamaji Masatsugu; Neal Joel W; Burt Bryan M*
来源:Annals of Thoracic Surgery, 2015, 99(1): E7-E9.
DOI:10.1016/j.athoracsur.2014.10.028

摘要

A 30-year-old man presented with rapidly progressive cerebellar symptoms. Brain magnetic resonance imaging was consistent with cerebellitis. A subsequent chest computed tomography revealed a multilobulated anterior mediastinal mass, which was diagnosed on the surgical biopsy specimen as hyaline vascular Castleman disease. After resection of the mediastinal mass and multiple involved adjacent mediastinal lymph nodes, the cerebellitis resolved. To the best of our knowledge, this is the first report of Castleman disease associated with cerebellitis. This rare case of suspected paraneoplastic cerebellitis related to a multifocal unicentric Castleman disease confined to the mediastinum is discussed.

  • 出版日期2015-1