Discovery of an orthoreovirus in the aborted fetus of a Steller sea lion (Eumetopias jubatus)

作者:Palacios Gustavo*; Wellehan James F X Jr; Raverty Stephen; Bussetti Ana V; Hui Jeffrey; Savji Nazir; Nollens Hendrik H; Lambourn Dyanna; Celone Christopher; Hutchison Stephen; Calisher Charles H; Nielsen Ole; Lipkin W Ian
来源:Journal of General Virology, 2011, 92: 2558-2565.
DOI:10.1099/vir.0.032649-0

摘要

An aborted mid-gestational male Steller sea lion fetus with an attached placenta was recovered on the floor of an open floating capture trap located off Norris Rock near Denman Island, British Columbia. Viral culture of the placenta demonstrated cytopathic effect. Although no specific signal was obtained in microarray experiments using RNA obtained from viral culture, elution and sequence analysis revealed the presence of a reovirus. Complete genome pyrosequencing led to the identification of an orthoreovirus that we have tentatively named Steller sea lion reovirus (SSRV). Phylogenetic analysis revealed similarities between SSRV and orthoreoviruses of birds, bats and other mammals that suggests potential for interspecies transmission.

  • 出版日期2011-11