科研之友
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摘要
In this review, we aimed to study the pharmacological profile, efficacy, and tolerability and safety data of asenapine, a drug approved in Turkey, in the treatment of schizophrenia and manic and mixed episodes of bipolar I disorder. As an antipsychotic drug with a low side effect profile (weight gain and other effects on glucose metabolism and lipid panel), asenapine is effective in the treatment of the positive symptoms of schizophrenia as well as the manic or mixed episodes associated with bipolar I disorder. Different mechanisms of action of new drug entities hold out hopes for improved treatment in psychopharmacotherapy.
- 出版日期2013-3
