Diffusion-Weighted and Magnetization Transfer Imaging in Testicular Spermatogenic Function Evaluation: Preliminary Results

作者：Wang, Huanjun; Guan, Jian^*; Lin, Jinhua; Zhang, Zhongwei; Li, Shurong; Guo, Yan; Cai, Huasong

来源：Journal of Magnetic Resonance Imaging, 2018, 47(1): 186-190.

DOI：10.1002/jmri.25732

• diffusion weighted imaging
• magnetization transfer imaging
• magnetic resonance imaging
• testicular
• spermatogenic function

PurposeTo assess the use of functional magnetic resonance imaging (MRI), including diffusion-weighted MRI (DWI) and magnetization transfer MRI (MTI) in evaluating male infertility. @@@ Materials and MethodsSixteen men with testicular spermatogenesis hypofunction confirmed by percutaneous testis biopsy and 31 volunteers (control group B, age range: 20-40 years) with normal semen analysis including younger (By, n = 15, age range: 20-30 years) and older (Bo, n = 16, age range: 31-40 years) men underwent pelvic 3T MRI, including DWI and MTI. Apparent diffusion coefficient (ADC) and magnetization transfer ratio (MTR) were compared. @@@ ResultsThe ADCs in 32 testes of 16 patients (0.497 0.037 x 10(-3) mm(2)/s) were significantly (P < 0.001) higher than that of control group B (0.460 0.031 x 10(-3) mm(2)/s), group By (0.453 0.018 x 10(-3) mm(2)/s), and group Bo (0.461 0.034 x 10(-3) mm(2)/s), whereas the MTRs were significantly lower than that of group B (16.14 +/- 4.20), group By (17.88 +/- 2.00), and group Bo (15.09 +/- 4.28) (P < 0.001). @@@ ConclusionFunctional MRI, including DWI and MTI, appears promising for evaluating male infertility with higher ADC and lower MTR in testicular spermatogenesis hypofunction. Level of Evidence: 2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018;47:186-190.

• 出版日期2018-1
• 单位中山大学