Posterior Reversible Encephalopathy Syndrome With Spinal Cord Involvement in Children: Clinicoradiologic Findings and a Retrospective Comparison Between Adult and Pediatric Patients

作者：Chen Tai Heng^*; Lin Wei Chen; Kao Wei Tsun; Tseng Chien Ming; Tseng Yong Hao

来源：Journal of Child Neurology, 2017, 32(1): 112-119.

DOI：10.1177/0883073816671237

• posterior reversible encephalopathy syndrome with spinal cord involvement
• childhood
• cerebrovascular disorders
• atypical manifestations

We characterized a cohort of patients with posterior reversible encephalopathy syndrome with spinal cord involvement. We encountered 2 children and identified an additional 19 patients from the internet databases. Of the 21 patients analyzed, 8 were children. The mean peak systolic blood pressure in adults was significantly higher than in children (221.8 +/- 14.3 vs 191.4 +/- 31.3 mm Hg; P <.01). Regardless of age, the most common clinical symptom was headache (90%) and the least common clinical symptom was seizures (28%). Atypical neuroimaging was more common in children (63%) than in adults (8%). Abnormal cerebrospinal fluid results were frequently found in children (83%). All children recovered uneventfully, but 3 adults had sequelae. A broader clinicoradiologic spectrum makes the diagnosis of children more complex than in adults. Awareness of the atypical features with a meticulous management of hypertension is imperative to avoid unnecessary invasive workups and to achieve an uneventful recovery.

• 出版日期2017-1