A One-Pot Multicomponent 1,3-Dipolar Cycloaddition Strategy: Combinatorial Synthesis of Dihydrothiophenone-Engrafted Dispiro Hybrid Heterocycles

作者：Rani Mani Anusha; Kumar Sundaravel Vivek; Malathi Karuppiah; Muthu Muthumani; Almansour Abdulrahman I; Kumar Raju Suresh; Kumar Raju Ranjith

来源：ACS Combinatorial Science, 2017, 19(5): 308-314.

DOI：10.1021/acscombsci.6b00186

• 1,3-dipolar cycloaddition
• azomethine ylide
• dihydrothiophen-3(2H)-ones
• dispiro heterocycles
• multicomponent reaction

The combinatorial syntheses of a library of novel dihydrothiophenone-engrafted dispiro oxindole/indenoquinoxaline-pyrrolidine/pyrrolothiazole/indolizine hybrid heterocycles have been realized through a chemo-, regio-, and stereoselective multicomponent 1,3-dipolar cycloaddition strategy.

• 出版日期2017-5