摘要

Some bifunctional heterocyclic systems having vicinal chlorocyano, chloroacetyl, and chloro-ethoxycarbonyl groups in their structures reacted with 6-amino-1,3-dimethyluracil to afford novel triheterocyclic systems having a pyrimidinedione moiety. Enaminones and alpha-cyanocinnamic acid derivatives in this reaction gave pyrido[2,3-d]pyrimidinediones. The antimicrobial activity of some new synthesized triheterocyclic systems was studied.

  • 出版日期2010-7